Search results for " polycarbonates"

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GALACTOSE-DECORATED POLYMERIC CARRIERS FOR HEPATOCYTE-SELECTIVE DRUG TARGETING

2015

In this paper, the current available strategies to realize galactose-decorated nanostructured polymeric systems are summarized. These carriers are designed in order to obtain targeted drug delivery to hepatocytes via galactose (GAL) moieties, i.e., for the treatment of viral hepatitis or liver cancer that are the greater causes of global disability and mortality. Usually, the main followed strategy to obtain galactosylated polymeric carriers is to use galactosylated copolymers. The chemical modifications of preformed polymers with sugar-containing reagents is followed for obtaining lactosaminated human albumin, galactosylated phospholipid-polyaminoacid and polylactide (PLA)- polyaminoacid c…

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoAsialoglycoprotein receptor (ASGP-R) carboxymethyl chitosan (CMC) galactose (GAL) hepatocytes lactosaminated albumin liver targeting poly(ε-caprolactone) (PCL) polyamidoamine (PAMAM) dendrimers polycarbonates polylactide (PLA) xyloglucan αβ-poly(N-2-hydroxyethyl)-DLaspartamide (PHEA).

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